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The company then was known as Kinetic Concepts; the name was changed to Acelity LP almost a year ago. At the time of the transaction, Kinetic Concepts had about 7, employees, including 2, in San Antonio. Today, Acelity LP has about 5, workers, including about 1, locally.
Private equity firms are known for squeezing costs out of a business in preparation for selling it for more money or taking it public. They generally look to exit a business within five years of acquiring it. This would mark the third public offering for the San Antonio company, through one reiteration or another.
Kinetic Concepts first went public in Nine years later, it was taken private by two investment banks and company founder Dr. James Leininger. Under the new ownership group, U. The results for both periods were affected by interest payments. Uvalde massacre ripples through small towns on Highway Uvalde now stands for grief, sadness and death, just like Columbine, Newtown and Parkland.
In CLL, the body becomes easily susceptible to infection because the "bad" white cells crowd out normal white cells, which are essential for fighting infection. About a third of those, that is roughly people, died from the disease note: doesn't imply new cases died in the same year.
The average age for CLL to be diagnosed is 71, and it is rarer for those under 40, almost nonexistent for the pediatric population. The first line of treatment for CLL has long been chemotherapy, including drugs like fludaribine Fludara, available since , a purine analog, alkylating agents, corticosteroids, and other cytotoxic agents. Since these drugs attack fast growing cells, normal fast growing cells are also affected, leading to hair loss, sores of the mouth lining, effects on normal bone marrow cells etc.
In recent times, monoclonal antibodies, which are artificially created immune system antibodies, have been developed to fight CLL both in early stages and when the disease is no longer responding to chemo. Two other new drugs are Obinutuzumab Gazyva and Ofatumumab Arzerra which are used in combination with chemo agent chlorambucil to target CD Gazyva is owned by Roche.
Some of these drugs are also used for multiple sclerosis. Besides these, there are also newly approved drugs ibrutinib and idelalisib, which have been approved very recently. The sell-off was seen by many as an excellent buying opportunity.
However, this should not be seen as a negative. Insiders can sell for any number of reasons. What investors should focus on is Gilead's strong fundamentals. In addition, there is an expectation that Gilead will use some of its cash to make acquisitions. But if the company does have any plans to acquire, then this probably is the best time to do so, given the pullback in the biotech sector in the past few weeks.
Piper Jaffray Recommends Buying on Weakness - The pullback in the biotech sector has created an excellent buying opportunity. Piper Jaffray noted that all four companies have strong balance sheets to make it through upcoming value-driving events. I have been bullish on Arrowhead's prospects for a while, and initiated coverage on the company in March this year.
The company has an upcoming catalyst, which could possibly give a boost to the stock price. Valeant Pharma VRX received a supplementary addition for Xenazine, a vesicular monoamine transporter 2 VMAT inhibitor indicated for the treatment of chorea associated with Huntington's disease.
The drug was first approved in , lost its orphan drug status this month, and there are generic versions available. According to a Seeking Alpha article , "Since Xenazine's launch in the fourth quarter of , annual sales in the U. There were a few other additions and revisions to old drugs, but nothing of consequence. Europe has been silent this entire month. Merck MRK is undertaking a study to assess the effect of the addition of sitagliptin to metformin compared with the addition of dapagliflozin to metformin on hemoglobin A1c A1C over 24 weeks of treatment as well as the overall safety and tolerability of sitagliptin in comparison to that of dapagliflozin after 24 weeks of treatment.
This is a Phase 3 study enrolling patients and ending in April Januvia sitagliptin , approved in October , is the first diabetes drug in a new class called dipeptidyl peptidase 4 DPP-4 inhibitors. As per the study agreement, UMass Medical School will provide Enumeral with tissue samples and blood samples from subjects with melanoma who are being treated with Ipilimumab Yervoy. As per the agreement, Recipharm will be responsible for the supply of the remaining clinical trial material and ongoing future commercial supply.
As per the filing, ALDX may offer and sell shares of preferred stock, common stock, debt securities or warrants either separately or in units in one or more offerings in amounts, at prices and on terms that the company will determine from time to time.